The cavities were prepared and filled with the fluoride- and Sr-containing restorative materials (FSCMs) in extracted human molars. To quantitatively analyze the distribution of F and Sr, micro-particle-induced gamma/X-ray emission (PIGE/PIXE) technique was used. All three samples demonstrated a tendency towards increased fluoride uptake from fluoride-containing hypersensitivity desensitizers and a demineralization inhibition effect on root dentin.įluorine (F) and strontium (Sr) are key elements in the de- and remineralization of teeth. TMR analysis revealed that both HS and FV showed significantly lower integrated mineral loss values than the control group. µPIXE/PIGE analysis demonstrated that all sample groups showed increased fluoride uptake on the root surface. Dentin demineralization was analyzed using transverse microradiography (TMR) before and after pH cycling. Fluorine and calcium distributions in the carious lesions of each specimen were evaluated using proton-induced gamma emission (PIGE) and X-ray (PIXE) techniques, respectively. All surfaces of each specimen, except the polished surface, were covered with wax and immersed in an automatic pH cycling system for 2 weeks. Single sections were obtained from each specimen. Each material was applied to the demineralized root surface. Three different fluoride-containing materials, namely “MS Coat F” (MS), “MS Coat Hys Block Gel” (HS), and CTX2 Varnish (FV), were used herein. Five noncarious extracted human teeth were used to produce specimens. This study aimed to evaluate the effectiveness of sealing materials in inhibiting demineralization and increasing fluorine (F) uptake by acid-treated root surfaces. Several desensitizers routinely used clinically for dentin hypersensitivity are expected to inhibit demineralization.
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